Antiviral Potential Analysis of Jamblang Seed Essential Oil (Syzygium cumini) Using GCMS

Winarsih -; Diky Setya Diningrat; Ayu Nirmala Sari; Novita Sari Harahap; Kusdianti -

doi:10.082022/kalwedosains.v2i2.4644

Winarsih - Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Negeri Medan, Medan, Indonesia
Diky Setya Diningrat Jurusan Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Negeri Medan, Medan, Indonesia
Ayu Nirmala Sari Program Studi Biologi, Fakultas Sains dan Teknologi, UIN Ar-Raniry Banda Aceh, Indonesia
Novita Sari Harahap Jurusan Ilmu Keolahragaan, Fakultas Ilmu Keolahragaan, Universitas Negeri Medan, Medan, Indonesia
Kusdianti - Jurusan Biologi, Fakultas Pendidikan Matematika dan Ilmu Pengetahuan Alam, Universitas Pendidikan Indonesia, Bandung, Indonesia

DOI: https://doi.org/10.082022/kalwedosains.v2i2.4644

Keywords: Jamblang, GCMS, PubChem, In silico, Antiviral

Abstract

Jamblang (Syzygium cumini) essential oil is another form of extraction to explore its potential medicinal properties. This study aims to determine the content of bioactive compounds contained in seed essential oil using the Gas Chromatography Mass Spectophotometer (GCMS) approach. Jamblang seed essential oil is produced through a steam distillation process. The results of the GCMS analysis were evaluated using the MASSLAB program. The data obtained from the GCMS tool was then further analyzed using the PubChem NCBI database software (https://pubchem.ncbi.nlm.nih.gov/) and PASS online. The results of this study indicate that there are 61 phytochemical compounds in jamblang seed essential oil. Of the total bioactive compounds, there are 2 phytochemical compounds that are useful as antivirals, while those that have similarities above 80% are 10 compounds. The results of this study can be used as a basis for a program to develop the potential use of bioactive compounds in jamblang seed essential oil as an antiviral. In future research, it is necessary to analyze other plant parts and make comparisons to complete the existing database.

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