Evaluation of the Antimicrobial Efficacy of Hibiscus sabdariffa L. Antiperspirant Preparations Against Staphylococcus epidermidis

  • Fath Dwisari Medical Laboratory Technology Study Program, Politeknik Aisyiyah Pontianak, Jl. Ampera No.09, Pontianak 78116, Indonesia
  • Abdurraafi Maududi Dermawan Department of Pharmacy, Faculty of Medicine, Tanjungpura University, Jl. Prof. Dr. H. Hadari Nawawi, Pontianak 78124, Indonesia
  • Puspa Amalia Medical Laboratory Technology Study Program, Politeknik Aisyiyah Pontianak, Jl. Ampera No.09, Pontianak 78116, Indonesia
  • Tessa Nathalia Tjoadri Medical Laboratory Technology Study Program, Politeknik Aisyiyah Pontianak, Jl. Ampera No.09, Pontianak 78116, Indonesia
  • Nur Atika Rahma Medical Laboratory Technology Study Program, Politeknik Aisyiyah Pontianak, Jl. Ampera No.09, Pontianak 78116, Indonesia
DOI: https://doi.org/10.30598/ijcr.2025.13-fat
Keywords: Antiperspirant, Hibiscus sabdariffa L, Rosella, Staphylococcus epidermidis

Abstract

Commercial antiperspirant products commonly incorporate synthetic compounds, several of which have raised concerns due to their potential carcinogenicity. Moreover, the inclusion of natural antibacterial agents in these formulations remains limited. Hibiscus sabdariffa L. (Rosella), a plant rich in bioactive secondary metabolites, offers a promising natural alternative. This study aimed to evaluate the antibacterial efficacy of rosella-based antiperspirant formulations, particularly against Staphylococcus epidermidis, a key contributor to body odor. Three formulations (F1, F2, and F3) were developed and assessed based on several parameters: pH, organoleptic properties, homogeneity, spreadability, adhesiveness, and antibacterial activity against Staphylococcus epidermidis. The results demonstrated that the antiperspirant preparations complied with standard evaluation criteria. Furthermore, the antibacterial assay outcomes yielded statistically significant differences (p < 0.05) in the mean diameter of the inhibition zones, indicating that H. sabdariffa L. exhibited measurable antibacterial activity against S. epidermidis. These findings support the potential application of Rosella extract in developing natural and efficacious anti-perspirant products.

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Published
2025-09-15
How to Cite
(1)
Dwisari, F.; Dermawan, A. M.; Amalia, P.; Tjoadri, T. N.; Rahma, N. A. Evaluation of the Antimicrobial Efficacy of Hibiscus Sabdariffa L. Antiperspirant Preparations Against Staphylococcus Epidermidis. Indo. J. Chem. Res. 2025, 13, 121-127.
Issue
Vol 13 No 2 (2025): Edition for September 2025
Section
Research articles

Copyright (c) 2025 Fath Dwisari, Abdurraafi Maududi Dermawan, Puspa Amalia, Tessa Nathalia Tjoadri, Nur Atika Rahma

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