Senyawa Triterpenoid dari Ekstrak N-heksana Daun Kelor (Moringa oleifera Lamk.) dan Uji Aktivitas Antibakteri Terhadap Staphylococcus aureus dan Escherichia coli

Triterpenoid Compound From n-Hexane Extract of Kelor Leaves (Moringa oleifera Lamk.) And Antibacterial Activity Test Against Staphylococus aureus and Escherichia coli

  • Yuszda Salimi Department of Chemistry, Faculty of Mathematic and Natural Science, Gorontalo State University
  • Nurhayati Bialangi Department of Chemistry, Faculty of Mathematic and Natural Science, Gorontalo State University
  • Widysusanti Abdulkadir Department of Pharmacy, Faculty of Sport and Natural Healty, Gorontalo State University
  • Boima Ramses Parulian Sekolah Tinggi Analis Kimia Cilegon
DOI: https://doi.org/10.30598/ijcr.2019.7-par
Keywords: kelor, Moringa oleifera Lamk, triterpenoid

Abstract

Kelor plant (Moringa oleifera Lamk) is a plant that grows naturally in a tropical climate. During this decoction of pirdot leaves plants are used by the people as antimicroba. The purpose of this study was to isolate triterpenoid compound from ethyl acetate extract of kelor leaves. The sample extraction was performed by maceration method using methanol as a solvent. Fractionation used n-hexana and etil asetat as a solvent. The separation and purification of the compound was carried out by column chromatography method followed by stain pattern analysis with thin layer chromatography (TLC). Characterization and elucidation of pure compound structures using UV, IR, 1H-NMR, 12C-NMR, HSQC, HMBC, and 1H-1H COSY, and compared with various literatures. Based on the result of structural elusidation, the pure isolate obtained is a pentacyclic triterpenoid group compound with the molecular formula C30H50O and the name of 3-hydroxy, 20 (29) -en, lupenol. The triterpenoid compound of 3-hidroxy, 20 (29) -en, lupenol is the first isolated and reported from leaves of kelor plant.

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Published
2019-07-31
How to Cite
(1)
Salimi, Y.; Bialangi, N.; Abdulkadir, W.; Parulian, B. Senyawa Triterpenoid Dari Ekstrak N-Heksana Daun Kelor (Moringa Oleifera Lamk.) Dan Uji Aktivitas Antibakteri Terhadap Staphylococcus Aureus Dan Escherichia Coli. Indo. J. Chem. Res. 2019, 7, 32-40.
Issue
Vol 7 No 1 (2019): Edisi Bulan Juli (Edition For July)
Section
Research articles

Copyright (c) 2019 Yuszda Salimi, Nurhayati Bialangi, Widysusanti Abdulkadir, Boima Ramses Parulian

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