ELUDASI KOMPLEKSITAS BIOAKTIF EKSTRAK MANGROVE (Rhizophora sp.) MELALUI METODE KROMATOGRAFI CAIR KINERJA TINGGI UNTUK KESEHATAN MANUSIA
Abstract
Background : Youtefa Bay, located in Jayapura City, Papua, is renowned for its natural beauty and is a conservation area with a mangrove forest ecosystem. The mangroves in Youtefa Bay, such as Rhizophora sp., play a crucial role in maintaining environmental balance and supporting the livelihoods of the surrounding communities. However, the biochemical complexity of these mangrove extracts poses a unique challenge in understanding their health effects. The objective of this research is to explore and elucidate the bioactive complexity of mangrove extracts, particularly Rhizophora sp.
Methods: . The analytical method employed in this study is High-Performance Liquid Chromatography (HPLC). The results of this research show that Rhizophora sp.
Results: Mangroves in Youtefa Bay, Jayapura City, contain various bioactive compounds such as alkaloids, flavonoids, terpenoids, saponins, and tannins, which are beneficial to health. Alkaloids aid in stimulating the nervous system, regulating blood pressure, and combating microbial infections. Flavonoids function as antibacterial and antioxidant agents, while terpenoids possess anti-inflammatory properties. Saponins are effective for the treatment of leukemia, asthma, rheumatism, and also exhibit anti-inflammatory effects. Tannins serve as anti-diarrheal, antioxidant, antibacterial, and astringent agents.
Conclusion: Mangrove Rhizophora sp. has various active compounds which are very beneficial for health, so it is necessary to preserve the mangrove ecosystem in Youtefa Bay, Jayapura City.
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References
Akram, A. M., & Hasnidar, H. (2022). Identifikasi Kerusakan Ekosistem Mangrove Di Kelurahan Bira Kota Makassar. JOURNAL OF INDONESIAN TROPICAL FISHERIES (JOINT-FISH) : Jurnal Akuakultur, Teknologi Dan Manajemen Perikanan Tangkap, Ilmu Kelautan, 5(1), 1–11. https://doi.org/10.33096/joint-fish.v5i1.101
Annisa. (2023). Aktivitas Antimikroba Ekstrak Infusa Daun Bakau Rhizopora. 6, 1–6. https://doi.org/10.31957//acr.v6i2.3412
Desa, N., Pesawaran, S., & Lampung, P. (1980). 7) 健常人の下肢血流と下肢サーモグラムの関係(日本医学生物学サーモグラフィ研究会(1)). Japanes Journal of Medical Instrumentation, 50(9), 473–474. https://doi.org/10.4286/ikakikaigaku.50.9_473_2
Dewi, M. S., Tri Nuraini, R. A., Yulianto, B., & Sibero, M. T. (2023). Kandungan Senyawa Bioaktif dan Aktivitas Biologis Daun Mangrove Lumnitzera racemosa di Pantai Teluk Awur dan Pantai Blebak Jepara. Journal of Marine Research, 12(3), 391–402. https://doi.org/10.14710/jmr.v12i3.34584
Hasibuan, N. E., & Sumartini, S. (2020). Potensi Ekstrak Daun Mangrove Rhizophora Mucronata Dan Avicennia Officinalis Sebagai Bahan Pembuatan Serbuk Effervescent. JSIPi (Jurnal Sains Dan Inovasi Perikanan) (Journal of Fishery Science and Innovation), 4(2), 74. https://doi.org/10.33772/jsipi.v4i2.12667
Henri, Syafaati, R., & Farhaby, M. (2023). Estimasi Cadangan Karbon Tersimpan pada Ekosistem Hutan Mangrove di Desa Kurau Timur, Kabupaten Bangka Tengah. Jurnal Hutan Dan Masyarakat, 15(1), 52–64. https://doi.org/10.24259/jhm.v15i1.24293
Islamiyati, R., Mugitasari, D. E., Nafiah, L. N., & Jayanto, I. (2024). Uji Aktivitas Antioksidan Ekstrak Etil Asetat Daun Matoa Menggunakan Radikal Bebas DPPH (Difenilpikrilhidrazil). 13, 611–618. https://doi.org/10.35799/pha.13.2024.55951
Issusilaningtyas, E., Azzahra, F., Nuur Rochmah, N., Ratna Faoziyah, A., & Puspo Aji, A. (2023). DAUN JERUJU (Acanthus ebracteatus Vahl). Jurnal Komunitas Farmasi Nasional, 3(2), 2023.
Karimah. (2017). Peran Ekosistem Hutan Mangrove Sebagai Habitat Untuk Organisme Laut. Jurnal Biologi Tropis, 17(2), 51–57. https://doi.org/10.29303/jbt.v17i2.497
Karunia. (2016). No 主観的健康感を中心とした在宅高齢者における 健康関連指標に関する共分散構造分析Title. 4(June), 2016.
Mahmiah, & Sudjarwo, G. W. (2019). Standardisasi Ekstrak Metanol Akar Mangrove Rhizophora mucronata Poiret dari Perairan Pantai Timur Surabaya. PROCEEDINGS OF THE 1 St STEEEM, 1(1), 371–376.
Manuhuttu, D., & Saimima, N. A. (2021). Potensi Daun Mangrove (Sonneratia alba) Sebagai Antibakteri Terhadap Salmonella, Staphylococcus aureus, dan Escherichia coli. Biopendix, 7(2), 71–79.
Prasetya, F., Bafadal, M., Fadilla, R., & Mus, N. M. (2024). Traditional Uses , Pharmacological Activities , and Bioactive Compounds of Mangroves Growing in Balikpapan Bay Penggunaan Tradisional , Aktivitas Farmakologis , Senyawa Bioaktif Mangrove yang Tumbuh di Teluk Balikpapan. 6(1).
Rahmah, W. (2021). Potensi Tanaman Mangrove Sebagai Agen Antikanker: Literature Review. Jurnal Penelitian Farmasi Indonesia, 10(1), 12–16. https://doi.org/10.51887/jpfi.v10i1.1168
Ramadhani, R. A., & Usman. (2021). Uji fitokimia dan toksisitas ekstrak metanol akar mangrove (Rhizophora mucronata) dengan metode brine shrimp lethality test (BSLT). Prosiding Seminar Nasional Kimia, 137–141.
Ramdana Sari* dan Retno Prayudyaningsih. (2018). Rhizobium : PEMANFAATANNYA SEBAGAI BAKTERI PENAMBAT NITROGEN Ramdana Sari * dan Retno Prayudyaningsih. 51–64.
Ramena, G. O., V Wuisang, C. E., & P Siregar, F. O. (2020). Pengaruh Aktivitas Masyarakat Terhadap Ekosistem Mangrove Di Kecamatan Mananggu. Jurnal Spasial, 7(3), 343–351.
Shofiana, I. (2020). Uji aktivitas antibakteri pada Bakteri Salmonella sp. dengan ekstrak kulit batang, daun dan buah Mangrove Sonneratia caseolaris. In Skripsi. http://digilib.uinsby.ac.id/id/eprint/43075
Sunani, S., & Hendriani, R. (2023). Classification and Pharmacological Activities of Bioactive Tannins. Indonesian Journal of Biological Pharmacy, 3(2), 130–136. https://jurnal.unpad.ac.id/ijbp
Supriatna, D., Mulyani, Y., Rostini, I., & Agung, M. U. K. (2019). Aktivitas Antioksidan, Kadar Total Flavonoid Dan Fenol Ekstrak Metanol Kulit Batang Mangrove Berdasarkan Stadia Pertumbuhannya. Jurnal Perikanan Dan Kelautan, 10(2), 35–42.
Swandi, H., Hadriyati, A., & Sanuddin, M. (2020). Validasi Dan Analisis Kadar Akrilamida Pada Kopi Tungkal Dengan Metode Kromatografi Cair Kinerja Tinggi (Kckt). Ekologia, 20(1), 40–44. https://doi.org/10.33751/ekologia.v20i1.1983

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