Screening Of Phytochemicals And Bioactivity Test Of The Leaves Breadfruit (Artocarpus altilis)

Skrining Fitokimia dan Uji Bioaktivitas Daun Sukun (Artocarpus altilis)

Abstract

Screening phytochemical and bioactivity test of breadfruit leaves (Arthocarpus altilis) have been done. The samples were used in the study extracted by maceration method with some solvent polarity enhanced, there are: n-hexane, chloroform, ethyl acetate, and methanol. The bioactivity test use BST (Brine Shrimp Lethality test). The activity assay use brine shrimp A. salina Leach. Content of the secondary metabolites in four crude extract of leaves of breadfruit (A. altilis) are alkaloids, steroids, terpenoids, and flavonoids. Whereas only phenolic compounds contained in the crude extract of chloroform and methanol. The saponins content only in the crude extract methanol. The fourth test of bioactivity of the crude extract of leaves of breadfruit there are: n-hexane, chloroform, ethyl acetate, and methanol had LC₅₀: > 1000 mg / mL; 387.436 mg / mL; 415.623 mg / mL; and 392.826 mg / mL respectively. The crude extract of chloroform, ethyl acetate, and methanol classified active in the BST test to brine shrimp A. salina, while the crude extract n-hexane classified as inactive. The Leaves of breadfruit (A. altilis) has potential to be used as medicine.