Synthesis Of Derivate Acetophenone From Fenol And Eugenol

Sintesis Senyawa Turunan Asetofeon Dari Fenol Dan Eugenol

  • Imanuel B. D. Kapelle Department of Chemistry, Faculty of Mathematics and Natural Science, University of Pattimura-Indonesia
  • Sabirin Matsjeh Department of Chemistry, Faculty of Mathematics and Natural Science, University of Gadjah Mada-Indonesia
Keywords: The synthesis, acylation, acetophenone, eugenol, Fries rearrangement

Abstract

The synthesis derivate acetophenone from fenol and eugenol had been carried out.  The acylation of fenol was performed by anhydride acetate and the fries rearrangement reaction was carried out using AlCl3 catalyst at temperature of 50oC produce ortho-hydroxyacetophenone (35,29 %), purity was tested by GC, structure elucidation of these product ware analized by FTIR and 1H-NMR. Acylation reaction of eugenol was performed by anhydride acetate in base condition at temperature of 120oC for 3 h produce 5-allyl-2-hydroxy-3-metoksi acetophenone (21,42%), purity was tested by GC, structure elucidation of these product ware analized by FTIR, 1H-NMR and MS.

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Published
2013-07-31
How to Cite
(1)
Kapelle, I.; Matsjeh, S. Synthesis Of Derivate Acetophenone From Fenol And Eugenol. Indo. J. Chem. Res. 2013, 1, 33-37.
Issue
Vol 1 No 1 (2013): Edisi Pertama (First Edition)
Section
Short communication

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