Synthesis Of 1-phenyl-4-(3’, 4’-dimethoxy phenyl)-1-Buten-3-on From Eugenol

Sintesis 1-fenil-4-(3’,4’-dimetoksi fenil)-1-buten-3-on dari Eugenol

  • Candra Y. Tahya Department of Chemistry, Faculty of Mathematics and Natural Science, University of Pattimura-Indonesia
  • Hanoch J. Sohilait Department of Chemistry, Faculty of Mathematics and Natural Science, University of Pattimura-Indonesia
  • Serly J. Sekewael Department of Chemistry, Faculty of Mathematics and Natural Science, University of Pattimura-Indonesia
Keywords: Eugenol, 1-phenyl-4-(3’, 4’-dimethoxy phenyl)-1-buten-3-on

Abstract

The synthesis of 1-phenyl-4-(3’, 4’-dimethoxy phenyl)-1-buten-3-one from eugenol has been done through four

reaction steps. The metilation of eugenol with dimethyl sulphate yields 81.81% of methyl eugenol.

Oxymercuration-demercuration of methyl eugenol with mercury acetate yields 67.27% of methyl eugenyl

alcohol. Oxidation of methyl eugenyl alcohol with pyridinium chloro chromate (PCC) yields 45.31% of methyl

eugenyl ketone. Aldol condensation reaction of methyl eugenyl ketone with benzaldehide catalyzed by potasium

hydroxyde yields 7.38% of 1-phenyl4-(3’,4’-dimethoxyphenyl)-1-buten-3-one. The purity of compounds was

tested by GC and LC. The Elucidation of structure was analyzed by FTIR, GC-MS, LC-ESI-MS, and

H-NMR.

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Published
2014-07-31
How to Cite
(1)
Tahya, C.; Sohilait, H.; Sekewael, S. Synthesis Of 1-Phenyl-4-(3’, 4’-Dimethoxy Phenyl)-1-Buten-3-on From Eugenol. Indo. J. Chem. Res. 2014, 2, 124-130.

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