Sintesis Fenetil (O-asetil-p-kumaroil) dari Asam p-kumarat melalui Asetilasi, Klorinasi dan Esterifikasi dengan Fenetilalkohol

Synthesis of Phenethyl (O-Acetyl-P-Coumaroyl) From P-Coumaric Acid Via Acetylation, Chlorination And Esterification With Phenethylalcohol

  • Bahja Bahja Department of Chemistry, Faculty of Mathematics and Natural Science, University of Hassanuddin-Indonesia
  • Firdaus Firdaus Department of Chemistry, Faculty of Mathematics and Natural Science, University of Hassanuddin-Indonesia
  • Nunuk H. Soekamto Department of Chemistry, Faculty of Mathematics and Natural Science, University of Hassanuddin-Indonesia
Keywords: Phenethyl (O-acetyl-p-coumaroyl), p-Coumaric acid, phenethylalcohol, esterification

Abstract

Synthesis of phenethyl (O-acetyl-p-coumaroyl) (4) from p-coumaric acid (1) using phenethylalcohol was succesfully conducted via acetylation (2), chlorination (3), and esterification (4). The acetylation was performed using acetic anhydride in pyridine at room temperature for 6 hours, the chlorination was performed using thionyl chloride in dry benzene by reflux at 75oC for 4 hours, continued with esterification by in situ using phenethylalcohol in dry dichloromethane at room temperature for 4 hours. The structure of each step reaction product was identified using FT-IR spectroscopy. The compound 2 was obtained as yellowish crystal with m.p 201-203oC and the compound 4 was obtained as white crystal with m.p 68-69oC.

 

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Published
2016-01-31
How to Cite
(1)
Bahja, B.; Firdaus, F.; Soekamto, N. Sintesis Fenetil (O-Asetil-P-Kumaroil) Dari Asam P-Kumarat Melalui Asetilasi, Klorinasi Dan Esterifikasi Dengan Fenetilalkohol. Indo. J. Chem. Res. 2016, 4, 335-338.
Section
Artikel singkat (Short communication)

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