STABILITY ANALYSIS OF A MATHEMATICAL MODEL OF RABIES SPREAD WITH VACCINATION IN HUMAN AND DOG POPULATIONS, INCLUDING AWARE AND UNAWARE EXPOSED SUBPOPULATIONS
Abstract
Rabies is a zoonotic disease that causes progressive and fatal inflammation of the brain and spinal cord, which can be prevented by vaccination. This study aims to analyze the stability of a mathematical model of rabies disease spread with vaccination in human and dog populations in Maluku Province. The model uses a system of ordinary differential equations that separates the human population into six subpopulations (6 variables) and the dog population into three subpopulations (3 variables). The new variables are unaware subpopulations that we divide from aware subpopulations. The results showed that disease-free and endemic equilibrium points could be achieved, and the stability of these equilibrium points was analyzed using basic reproduction numbers Both disease-free and endemic equilibrium points are locally asymptotically stable. The Numerical simulations were also conducted to determine the characteristics of each subpopulation. This study was to provide better insight into controlling the spread of rabies in Maluku Province and it can be used as a reference in developing mathematical models for other infectious diseases.
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Copyright (c) 2025 Maria Engeline Sahusilawane, Venn Yan Ishak Ilwaru, Yopi Andry Lesnussa, Lazarus Kalvein Beay, Mayowa Micheal Ojo, Vynska Amalia Permadi, Olumuyiwa James Peter
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